Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP4 | P49662 | 1/20 | 0.46 |
| ▸ | CASP5 | P51878 | 1/20 | 0.46 |
| ▸ | CDK4 | P11802 | 7/20 | 0.40 |
| ▸ | PIM1 | P11309 | 7/20 | 0.40 |
| ▸ | PIM3 | Q86V86 | 7/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 7/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 6/20 | 0.39 |
| ▸ | NMT1 | P30419 | 2/20 | 0.38 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30161962 | 1.00 | CASP1 (0.46) | CASP1CASP4CASP5CDK4PIM1 | |
| SCHEMBL24851850 | 0.91 | CDK4 (0.41) | CASP1CASP4CASP5CDK4PIM1 | |
| SCHEMBL30162131 | 0.91 | CDK4 (0.41) | CASP1CASP4CASP5CDK4PIM1 | |
| SCHEMBL30162034 | 0.81 | CASP1 (0.39) | CASP1CASP4CASP5EGFRERBB2 | |
| SCHEMBL24852015 | 0.81 | CASP1 (0.39) | CASP1CASP4CASP5EGFRERBB2 | |
| SCHEMBL24851285 | 0.80 | PIM1 (0.45) | CASP1CASP4CASP5PIM1PIM3 | |
| SCHEMBL30161933 | 0.79 | CDK4 (0.45) | CASP1CASP4CASP5CDK4PIM1 | |
| SCHEMBL24851155 | 0.79 | CDK4 (0.45) | CASP1CASP4CASP5CDK4PIM1 | |
| SCHEMBL24851179 | 0.78 | CDK4 (0.49) | CASP1CASP4CASP5CDK4PIM1 | |
| SCHEMBL30162044 | 0.78 | CDK4 (0.49) | CASP1CASP4CASP5CDK4PIM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |