Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | PDE4A | P27815 | 3/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | GAA | P10253 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | CASP1 | P29466 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAD52 | P43351 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851761 | 0.78 | CHRM3 (0.42) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24851454 | 0.77 | CHRM3 (0.45) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24851478 | 0.75 | CHRM3 (0.55) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL9163278 | 0.73 | CASP1 (0.53) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24851956 | 0.71 | HRH4 (0.36) | L3MBTL1ALDH1A1TDP1SMN1; SMN2CYP1A2 | |
| SCHEMBL24851308 | 0.71 | CHRM3 (0.53) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3410886 | 0.71 | CRHBP (0.64) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24852361 | 0.70 | SLC29A1 (0.39) | KDM4EALDH1A1CASP1SMN1; SMN2CYP1A2 | |
| SCHEMBL4116293 | 0.70 | CYP1A2 (0.48) | CHRM3PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3236763 | 0.70 | CYP1A2 (0.48) | CHRM3PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |