Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24852361 | 0.83 | SLC29A1 (0.39) | HRH4SMN1; SMN2CYP1A2LMNATSHR | |
| SCHEMBL24851443 | 0.79 | HRH4 (0.35) | HRH4ALDH1A1 | |
| SCHEMBL24851957 | 0.78 | NAPEPLD (0.40) | L3MBTL1FFAR4SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL9163278 | 0.72 | CASP1 (0.53) | HRH4SMN1; SMN2CYP1A2LMNATSHR | |
| SCHEMBL24851760 | 0.71 | CHRM3 (0.41) | HRH4L3MBTL1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL19631330 | 0.70 | KMT2A (0.44) | SIGMAR1SMN1; SMN2CYP1A2LMNAKMT2A | |
| SCHEMBL24851478 | 0.70 | CHRM3 (0.55) | HRH4L3MBTL1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL12486712 | 0.70 | SMN1; SMN2 (0.41) | HRH4L3MBTL1SMN1; SMN2CYP1A2LMNA | |
| SCHEMBL6432855 | 0.69 | CASP1 (0.46) | HRH4KMT2ACYP2C9CYP2C19 | |
| SCHEMBL3405363 | 0.68 | CRHBP (0.61) | HRH4L3MBTL1SMN1; SMN2CYP1A2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |