Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.39 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP4 | P49662 | 1/20 | 0.33 |
| ▸ | CASP5 | P51878 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851956 | 0.83 | HRH4 (0.36) | HRH4SMN1; SMN2ALDH1A1KMT2ALMNA | |
| SCHEMBL24852362 | 0.79 | SLC29A1 (0.42) | SLC29A1PDE10AMAPTROCK2ROCK1 | |
| SCHEMBL23299902 | 0.74 | NAPEPLD (0.43) | SMN1; SMN2ALDH1A1KMT2ACYP1A2KDM4E | |
| SCHEMBL9640137 | 0.73 | SLC29A1 (0.47) | SLC29A1PDE10AMAPTHRH4SMN1; SMN2 | |
| SCHEMBL20710517 | 0.72 | GBA1 (0.46) | SMN1; SMN2ALDH1A1KMT2ALMNATSHR | |
| SCHEMBL9163278 | 0.71 | CASP1 (0.53) | HRH4SMN1; SMN2KMT2ACASP1CASP4 | |
| SCHEMBL24851760 | 0.70 | CHRM3 (0.41) | HRH4SMN1; SMN2ALDH1A1KMT2ACASP1 | |
| SCHEMBL16506138 | 0.69 | LMNA (0.50) | LMNAKDM4ECYP3A4DPP4 | |
| SCHEMBL18036125 | 0.69 | SMN1; SMN2 (0.46) | HRH4SMN1; SMN2ALDH1A1CASP1CASP4 | |
| SCHEMBL24851478 | 0.69 | CHRM3 (0.55) | HRH4SMN1; SMN2ALDH1A1KMT2ACASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |