Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.52 |
| ▸ | IDH1 | O75874 | 11/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31192189 | 0.84 | IDH1 (0.52) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL24851987 | 0.84 | IDH1 (0.52) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL30162723 | 0.75 | IL4I1 (0.51) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL24851981 | 0.75 | IL4I1 (0.51) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL29950401 | 0.71 | IDH1 (0.51) | IDH1 | |
| SCHEMBL24851779 | 0.71 | IDH1 (0.44) | IL4I1IDH1 | |
| SCHEMBL24851978 | 0.70 | KDM4E (0.46) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL30162617 | 0.69 | IL4I1 (0.66) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL24851732 | 0.69 | IL4I1 (0.66) | IL4I1IDH1PDE10AKDM4EALDH1A1 | |
| SCHEMBL24851742 | 0.69 | KDM4E (0.46) | IL4I1IDH1PDE10AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |