Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 9/20 | 0.51 |
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | DDO | Q99489 | 1/20 | 0.44 |
| ▸ | TNKS | O95271 | 1/20 | 0.43 |
| ▸ | KDR | P35968 | 2/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.39 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.38 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20547348 | 0.77 | BRD4 (0.46) | IDH1BRD4DAODDOKDR | |
| SCHEMBL4543934 | 0.74 | BRD4 (0.50) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL9686105 | 0.74 | BRD4 (0.50) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL6582983 | 0.73 | BRD4 (0.49) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL24851987 | 0.72 | IDH1 (0.52) | IDH1PARP1 | |
| SCHEMBL31192189 | 0.72 | IDH1 (0.52) | IDH1PARP1 | |
| SCHEMBL27946461 | 0.72 | ALDH1A1 (0.43) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL3459225 | 0.72 | HRH4 (0.51) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL31149055 | 0.72 | HRH4 (0.51) | BRD4DAODDOKDRCHEK1 | |
| SCHEMBL138181 | 0.72 | KEAP1 (0.44) | TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | claimed |
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | disclosed |
| CN-113185505-B | Quinolone oxazolidinone compound and preparation method and application thereof | 中国农业大学 | 2022-09-27 | — | — | CN | disclosed |