Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NAPEPLD | Q6IQ20 | 7/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.38 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.38 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.38 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851957 | 0.83 | NAPEPLD (0.40) | NAPEPLDEHMT2EHMT1MAPTLMNA | |
| SCHEMBL24852361 | 0.79 | SLC29A1 (0.39) | SLC29A1DPP4CYP3A4PDE10AMAPT | |
| SCHEMBL2982745 | 0.75 | L3MBTL1 (0.40) | MAPTLMNAKMT2A | |
| SCHEMBL24851761 | 0.70 | CHRM3 (0.42) | EHMT2EHMT1LMNAKMT2A | |
| SCHEMBL9640137 | 0.68 | SLC29A1 (0.47) | SLC29A1PDE10AMAPTKMT2A | |
| SCHEMBL3406103 | 0.67 | KMT2A (0.54) | MAPTKMT2A | |
| SCHEMBL30161966 | 0.67 | CKS1B (0.43) | NAPEPLDMAPTLMNAKMT2A | |
| SCHEMBL2771738 | 0.66 | CYP1A2 (0.47) | MAPTLMNAKMT2A | |
| SCHEMBL16094927 | 0.66 | CYP1A2 (0.60) | MAPTLMNAKMT2A | |
| SCHEMBL2955939 | 0.66 | MEN1 (0.44) | LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278483-A1 | COMPOUNDS HAVING 1H-PYRAZOLO[4,3-C]PYRIDIN-6-AMINOS AS THERAPEUTIC AGENTS | LOMOND THERAPEUTICS, INC. (US) | 2023-01-05 | — | — | WO | disclosed |