Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.56 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851784 | 0.86 | IL4I1 (0.60) | IL4I1NPSR1TSHRKDM4EALDH1A1 | |
| SCHEMBL24851962 | 0.83 | IL4I1 (0.51) | IL4I1EGFRERBB2LMNAMAPT | |
| SCHEMBL24852008 | 0.81 | GUSB (0.51) | IL4I1EGFRERBB2NPSR1KDM4E | |
| SCHEMBL24852507 | 0.80 | IL4I1 (0.51) | IL4I1EGFRNPSR1MEN1TSHR | |
| SCHEMBL24851920 | 0.79 | IL4I1 (0.47) | IL4I1EGFRERBB2NPSR1MEN1 | |
| SCHEMBL24852000 | 0.78 | EGFR (0.55) | IL4I1EGFRERBB2NPC1RAB9A | |
| SCHEMBL24851911 | 0.78 | IL4I1 (0.46) | IL4I1EGFRERBB2TSHRKDM4E | |
| SCHEMBL24851925 | 0.77 | IL4I1 (0.46) | IL4I1NPSR1MEN1LMNATSHR | |
| SCHEMBL24851914 | 0.76 | IDO1 (0.48) | IL4I1EGFRTSHRKDM4EALDH1A1 | |
| SCHEMBL24852502 | 0.76 | KDM4E (0.45) | IL4I1EGFRMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |