Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL4I1 | Q96RQ9 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.40 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | APAF1 | O14727 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24851922 | 0.89 | IL4I1 (0.44) | IL4I1ALDH1A1KDM4ETSHRCYP3A4 | |
| SCHEMBL24851962 | 0.83 | IL4I1 (0.51) | IL4I1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL24851925 | 0.81 | IL4I1 (0.46) | IL4I1ALDH1A1KDM4ETSHRCYP3A4 | |
| SCHEMBL24852008 | 0.81 | GUSB (0.51) | IL4I1ALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL24852003 | 0.81 | ALDH1A1 (0.48) | IL4I1ALDH1A1KDM4ETSHRCYP3A4 | |
| SCHEMBL24852507 | 0.80 | IL4I1 (0.51) | IL4I1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL24852499 | 0.80 | IL4I1 (0.44) | IL4I1ALDH1A1KDM4ETSHRCYP3A4 | |
| SCHEMBL24852501 | 0.79 | IL4I1 (0.56) | IL4I1ALDH1A1KDM4ETSHRHPGD | |
| SCHEMBL24852000 | 0.78 | EGFR (0.55) | IL4I1ALDH1A1TSHRHPGDHSD17B10 | |
| SCHEMBL24851911 | 0.78 | IL4I1 (0.46) | IL4I1ALDH1A1KDM4ETSHRHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023278222-A1 | IL4I1 INHIBITORS AND METHODS OF USE | MERCK SHARP & DOHME LLC (US) | 2023-01-05 | — | — | WO | disclosed |