Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 8/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RORC | P51449 | 2/20 | 0.38 |
| ▸ | ABL1 | P00519 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 1/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2487464 | 0.92 | ACHE (0.44) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL12206938 | 0.87 | ACHE (0.36) | ACHEALDH1A1PKMHTTABL1 | |
| SCHEMBL2313625 | 0.87 | CSNK1D (0.39) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2321338 | 0.86 | ACHE (0.39) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2487593 | 0.85 | ALDH1A1 (0.46) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2314979 | 0.85 | ALDH1A1 (0.41) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2490939 | 0.85 | RORC (0.41) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2484976 | 0.84 | ALDH1A1 (0.45) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2485003 | 0.84 | RORC (0.42) | ACHEALDH1A1PKMHTTRORC | |
| SCHEMBL2490686 | 0.84 | SMN1; SMN2 (0.45) | ALDH1A1PKMRORCMAPTPTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2380631-A1 | Heteroaryl derivatives as DGAT1 inhibitors | Novartis AG (CH) | 2011-10-26 | — | — | EP | disclosed |