SCHEMBL24858766

SCHEMBL24858766

Cc1ccc(C(c2ccc(OC#N)cc2)(C(F)(F)F)C(F)(F)F)cc1

nearest known ligand 0.39

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
AR P10275 8/20 0.39
ESR1 P03372 1/20 0.38
ESR2 Q92731 1/20 0.38
HTR2A P28223 1/20 0.35
SLC6A4 P31645 1/20 0.35
KCNH2 Q12809 1/20 0.35
MLYCD O95822 1/20 0.34
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA5A P35218 1/20 0.33
CA9 Q16790 1/20 0.33
TSHR P16473 1/20 0.33
ACHE P22303 1/20 0.33
KIF11 P52732 2/20 0.33
ALDH1A1 P00352 1/20 0.32
CYP2A6 P11509 1/20 0.32
RORC P51449 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24990 0.91 ESR1 (0.45) ARESR1ESR2KIF11
SCHEMBL24858767 0.84 ESR1 (0.39) ESR1ESR2KCNH2TSHRKIF11
SCHEMBL764016 0.81 ACHE (0.48) ARCA1CA2CA9TSHR
SCHEMBL275843 0.80 TEAD4 (0.48) ARESR1ESR2HTR2ASLC6A4
SCHEMBL9741002 0.80 TEAD4 (0.48) ARESR1ESR2HTR2ASLC6A4
SCHEMBL275315 0.79 ESR1 (0.56) ESR1ESR2MLYCDCA1CA2
SCHEMBL25919760 0.79 ESR1 (0.56) ESR1ESR2MLYCDCA1CA2
SCHEMBL9914241 0.78 ACHE (0.60) ESR1ESR2CA1CA2CA9
SCHEMBL13084705 0.78 CYP3A4 (0.36) ESR1ESR2TSHR
SCHEMBL19771205 0.75 TEAD4 (0.52) ARTSHRACHEALDH1A1CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11552010-B2 Dielectric for high density substrate interconnects INTEL CORPORATION (US) 2023-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11552010-B2 Dielectric for high density substrate interconnects EPCAM, ICAM1, ILK AR 3854/4885ESR1 310/4885ESR2 1322/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.