SCHEMBL2485883

SCHEMBL2485883

Oc1ccccc1Nc1ccccn1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.73
MEN1 O00255 4/20 0.73
MAPK10 P53779 1/20 0.73
GFER P55789 1/20 0.73
RAB9A P51151 6/20 0.54
NPC1 O15118 6/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
KDM4E B2RXH2 1/20 0.54
LMNA P02545 1/20 0.54
TP53 P04637 1/20 0.54
ALOX15 P16050 1/20 0.54
TSHR P16473 1/20 0.54
ALOX12 P18054 1/20 0.54
HTT P42858 1/20 0.54
KLF5 Q13887 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
ALDH1A1 P00352 1/20 0.51
HPGD P15428 1/20 0.51
GAA P10253 3/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27999264 0.87 KMT2A (0.66) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL3279571 0.85 MEN1 (1.00) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL2501726 0.78 KMT2A (0.70) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL221242 0.78 KMT2A (0.76) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL29391624 0.78 KMT2A (0.76) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL30167997 0.78 MEN1 (0.76) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL3265731 0.78 MEN1 (0.76) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL32674561 0.77 MAPK10 (0.53) KMT2AMEN1MAPK10GFERL3MBTL1
SCHEMBL7985717 0.76 KMT2A (0.73) KMT2AMEN1MAPK10GFERRAB9A
SCHEMBL7941542 0.76 MAPK10 (0.73) KMT2AMEN1MAPK10GFERRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-63039862-A None JP disclosed
US-12250875-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2025-03-11 US disclosed
US-20240122061-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-04-11 US disclosed
US-11930699-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-03-12 US disclosed
CN-112390829-A Organic electroluminescent material and device 环球展览公司 2021-02-23 CN disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2021-02-18 US disclosed
EP-2376455-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS Amgen Inc. (US) 2011-10-19 EP disclosed
WO-2010077992-A1 AMINOPYRIDINE AND CARBOXYPYRIDINE COMPOUNDS AS PHOSPHODIESTERASE 10 INHIBITORS AMGEN INC. (US) 2010-07-08 WO disclosed
JP-S6339862-A PYRIDYLAMINOPHENOL DERIVATIVE OTSUKA PHARMACEUT FACTORY INC 1988-02-20 JP disclosed
US-4297363-A 2-Amino-3(4 or 5)-(pyridinyl)phenols and their use as cardiotonics STERLING DRUG INC. (US) 1981-10-27 US disclosed
US-3960886-A Substituted N-arylanilines STERLING DRUG INC. (US) 1976-06-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12250875-B2 Organic electroluminescent materials and devices L1CAM, SOD1, EPCAM KMT2A 3799/4885MEN1 1625/4885MAPK10 1412/4885
US-11930699-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, LEF1 KMT2A 3150/4885MEN1 961/4885MAPK10 1988/4885
US-20210050532-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, LEF1 KMT2A 3150/4885MEN1 961/4885MAPK10 1988/4885
US-20240122061-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, SOD1, EPCAM KMT2A 3799/4885MEN1 1625/4885MAPK10 1412/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.