SCHEMBL24858846

SCHEMBL24858846

Cc1cccc2c1Sc1c(C)ccnc1C2

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
PSMD14 O00487 1/20 0.31
COPS5 Q92905 1/20 0.31
HDAC8 Q9BY41 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5542608 0.74 MEN1 (0.46) MEN1KMT2AHDAC8
SCHEMBL24858827 0.72 PSMD14 (0.33) PSMD14COPS5
SCHEMBL9168368 0.69 KMT2A (0.50) MEN1KMT2A
SCHEMBL13113542 0.68 MEN1 (0.66) MEN1KMT2AHDAC8
SCHEMBL28520715 0.67 KMT2A (0.55) MEN1KMT2A
SCHEMBL1869137 0.66 METAP2 (0.40) KMT2A
SCHEMBL27027257 0.66 NOS3 (0.38)
SCHEMBL18266927 0.64 NOS3 (0.41) MEN1KMT2A
SCHEMBL24858847 0.63 PDK2 (0.31) PSMD14COPS5
SCHEMBL1347881 0.63 KMT2A (0.48) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230122208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-04-20 US disclosed
US-11548905-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230122208-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES ZYX, SLC39A3, SOD3 MEN1 374/4885KMT2A 1019/4885PSMD14 3681/4885
US-11548905-B2 Organic electroluminescent materials and devices ZYX, SLC39A3, SOD3 MEN1 374/4885KMT2A 1019/4885PSMD14 3681/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.