Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 1/20 | 0.35 |
| ▸ | AOC2 | O75106 | 3/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.33 |
| ▸ | RORC | P51449 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 4/20 | 0.32 |
| ▸ | TYK2 | P29597 | 4/20 | 0.32 |
| ▸ | JAK3 | P52333 | 4/20 | 0.32 |
| ▸ | JAK1 | P23458 | 3/20 | 0.32 |
| ▸ | MMP2 | P08253 | 3/20 | 0.32 |
| ▸ | MMP9 | P14780 | 2/20 | 0.32 |
| ▸ | MMP14 | P50281 | 2/20 | 0.32 |
| ▸ | MMP3 | P08254 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.31 |
| ▸ | MAOB | P27338 | 2/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12695027 | 0.87 | CHRNA7 (0.40) | GLP1RAOC2KCNH2RORCJAK2 | |
| SCHEMBL12695032 | 0.81 | GLP1R (0.44) | GLP1RAOC2KCNH2RORCJAK2 | |
| SCHEMBL12697199 | 0.76 | JAK2 (0.47) | GLP1RAOC2KCNH2JAK2TYK2 | |
| SCHEMBL23103102 | 0.74 | PTGS1 (0.36) | GLP1RAOC2KCNH2RORCJAK2 | |
| SCHEMBL23089717 | 0.74 | KDM4E (0.49) | AOC2KCNH2JAK2TYK2JAK3 | |
| SCHEMBL23089272 | 0.74 | ALDH1A1 (0.51) | GLP1R | |
| SCHEMBL29736739 | 0.74 | ALDH1A1 (0.51) | GLP1R | |
| SCHEMBL23103090 | 0.72 | CHRNA7 (0.42) | GLP1RAOC2KCNH2RORCJAK2 | |
| SCHEMBL16172618 | 0.71 | AOC2 (0.46) | GLP1RAOC2KCNH2JAK2TYK2 | |
| SCHEMBL12481645 | 0.70 | KDM4E (0.46) | AOC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11548890-B1 | HPK1 antagonists and uses thereof | Nimbus Saturn, Inc. (US) | 2023-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11548890-B1 | HPK1 antagonists and uses thereof | PDXK, HIPK1, PCK1 | GLP1R 1293/4885AOC2 4563/4885KCNH2 4140/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.