SCHEMBL2486085

SCHEMBL2486085

COc1cc(C(=O)N(C)C)cc(OC)c1O

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PKM P14618 3/20 0.62
CA12 O43570 1/20 0.62
CA1 P00915 1/20 0.62
CA2 P00918 1/20 0.62
CA3 P07451 1/20 0.62
CA4 P22748 1/20 0.62
CA6 P23280 1/20 0.62
CA5A P35218 1/20 0.62
CA7 P43166 1/20 0.62
CA9 Q16790 1/20 0.62
CA14 Q9ULX7 1/20 0.62
CA5B Q9Y2D0 1/20 0.62
LMNA P02545 1/20 0.62
ERN1 O75460 2/20 0.54
PTGS2 P35354 2/20 0.53
KMT2A Q03164 3/20 0.46
ALDH1A1 P00352 3/20 0.46
GAA P10253 2/20 0.46
KDM4E B2RXH2 1/20 0.46
CYP19A1 P11511 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7376402 0.84 TUBB4A (0.51) LMNAKMT2AALDH1A1KDM4ECYP3A4
SCHEMBL1004147 0.84 RXFP1 (0.53) PKMCA12CA1CA2CA3
SCHEMBL13286764 0.83 PKM (0.56) PKMCA12CA1CA2CA3
SCHEMBL24163458 0.82 PKM (0.55) PKMCA12CA1CA2CA3
SCHEMBL1545307 0.79 CYP1A2 (0.69) ERN1KMT2AALDH1A1GAAKDM4E
SCHEMBL15288999 0.79 PKM (0.72) PKMCA12CA1CA2CA3
SCHEMBL27905025 0.79 PKM (0.72) PKMCA12CA1CA2CA3
SCHEMBL6409033 0.78 CYP2C9 (0.66) CA12CA1CA2CA4CA6
Acetosyringone SCHEMBL15511 0.77 LMNA (1.00) PKMCA12CA1CA2CA3
Syringic Acid SCHEMBL27602358 0.77 CA12 (1.00) PKMCA12CA1CA2CA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8772005-B2 Laccases, compositions and methods of use DANISCO US INC. (US) 2014-07-08 US claimed
US-20120151682-A1 Novel Laccases, Compositions and Methods of Use DANISCO US INC. (US) 2012-06-21 US claimed
EP-2094842-B1 NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE DANISCO US INC (US) 2012-06-13 EP claimed
EP-2094842-A2 NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE Danisco US, INC., Genencor Division (US) 2009-09-02 EP claimed
US-20080196173-A1 Novel Laccases, Compositions And Methods of Use DANISCO US INC., GENENCOR DIVISION 2008-08-21 US claimed
WO-2008076322-A2 NOVEL LACCASES, COMPOSITIONS AND METHODS OF USE DANISCO US, INC., GENENCOR DIVISION (US) 2008-06-26 WO claimed
EP-2463336-B1 POLYVINYL ACETAL COMPOSITION, LAMINATE, AND USE THEREOF KURARAY CO (JP) 2019-10-02 EP disclosed
US-8282688-B2 Carboxyamido and cyano derivatives of 2,6-dimethoxyphenol that exhibit improved hydrolytic stability and good bleaching performance on denim fabrics DANISCO US INC. (US) 2012-10-09 US disclosed
EP-2463336-A1 POLYVINYL ACETAL COMPOSITION, LAMINATE, AND USE THEREOF Kuraray Co., Ltd. (JP) 2012-06-13 EP disclosed
EP-2376629-A1 LACCASES AND METHODS OF USE THEREOF AT LOW TEMPERATURE Danisco US Inc. (US) 2011-10-19 EP disclosed
WO-2010075402-A1 LACCASES AND METHODS OF USE THEREOF AT LOW TEMPERATURE DANISCO US INC. (US) 2010-07-01 WO disclosed
US-20080189871-A1 LACCASE MEDIATORS AND METHODS OF USE DANISCO US INC., GENENCOR DIVISION 2008-08-14 US disclosed
WO-2008076323-A2 LACCASE MEDIATORS AND METHODS OF USE DANISCO US, INC., GENENCOR DIVISION (US) 2008-06-26 WO disclosed