Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.40 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 6/20 | 0.37 |
| ▸ | CA2 | P00918 | 6/20 | 0.37 |
| ▸ | SIRT5 | Q9NXA8 | 3/20 | 0.36 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864590 | 0.85 | SIRT1 (0.40) | SIRT1SIRT2CA1CA2SIRT5 | |
| SCHEMBL24864439 | 0.84 | GLP1R (0.40) | GLP1RFOLH1 | |
| SCHEMBL24864619 | 0.82 | FOLH1 (0.40) | SIRT1SIRT2CA1CA2SIRT5 | |
| SCHEMBL24864470 | 0.82 | SIRT1 (0.39) | SIRT1SIRT2CA1CA2SIRT5 | |
| SCHEMBL24864395 | 0.79 | SIRT2 (0.38) | SIRT1SIRT2CA1CA2SIRT5 | |
| SCHEMBL24864633 | 0.78 | QRFPR (0.38) | SIRT1SIRT2CA1CA2SIRT5 | |
| SCHEMBL24864606 | 0.77 | SIRT2 (0.47) | SIRT1SIRT2SIRT5 | |
| SCHEMBL27291550 | 0.77 | FURIN (0.36) | GLP1RSIRT5FOLH1 | |
| SCHEMBL27291574 | 0.76 | FURIN (0.42) | SIRT1SIRT2CA1CA2SIRT5 | |
| SCHEMBL27291562 | 0.74 | FURIN (0.37) | SIRT1SIRT2CA1CA2SIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |