Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 9/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 9/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SIRT3 | Q9NTG7 | 3/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.37 |
| ▸ | CA1 | P00915 | 4/20 | 0.37 |
| ▸ | CA2 | P00918 | 4/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CA4 | P22748 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864619 | 0.93 | FOLH1 (0.40) | FURINSIRT2SIRT1FOLH1SIRT3 | |
| SCHEMBL24864395 | 0.85 | SIRT2 (0.38) | FURINSIRT2SIRT1FOLH1SIRT3 | |
| SCHEMBL27292223 | 0.84 | FAP (0.41) | FURINSIRT2SIRT1FOLH1SIRT3 | |
| SCHEMBL24864633 | 0.83 | QRFPR (0.38) | FURINSIRT2SIRT1FOLH1SIRT5 | |
| SCHEMBL24864590 | 0.82 | SIRT1 (0.40) | SIRT2SIRT1FOLH1SIRT3SIRT5 | |
| SCHEMBL24864470 | 0.80 | SIRT1 (0.39) | SIRT2SIRT1FOLH1SIRT3SIRT5 | |
| SCHEMBL27291528 | 0.80 | FURIN (0.49) | FURINSIRT2SIRT1KMT2AATM | |
| SCHEMBL24864606 | 0.79 | SIRT2 (0.47) | SIRT2SIRT1SIRT3SIRT5 | |
| SCHEMBL27291531 | 0.78 | FURIN (0.49) | FURINKMT2AATMCA1CA2 | |
| SCHEMBL24864394 | 0.76 | GLP1R (0.40) | SIRT2SIRT1FOLH1SIRT5CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240207429-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | WILMINGTON TRUST, NATIONAL ASSOCIATION | 2024-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240207429-A1 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PAICS, DHFR, CD44 | FURIN 34/4885SIRT2 1070/4885SIRT1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.