Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QRFPR | Q96P65 | 5/20 | 0.38 |
| ▸ | FURIN | P09958 | 3/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 4/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.35 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.35 |
| ▸ | ITGAV | P06756 | 1/20 | 0.35 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24864395 | 0.93 | SIRT2 (0.38) | FURINFOLH1SIRT2SIRT1SIRT5 | |
| SCHEMBL24864619 | 0.90 | FOLH1 (0.40) | FURINFOLH1SIRT2SIRT1SIRT5 | |
| SCHEMBL24864590 | 0.85 | SIRT1 (0.40) | FOLH1SIRT2SIRT1SIRT5CA1 | |
| SCHEMBL24864487 | 0.85 | KLKB1 (0.44) | QRFPRFURINCA1CA2ITGB1 | |
| SCHEMBL24864438 | 0.85 | FOLH1 (0.39) | FURINFOLH1SIRT2SIRT1SIRT5 | |
| SCHEMBL27291574 | 0.83 | FURIN (0.42) | FURINFOLH1SIRT2SIRT1SIRT5 | |
| SCHEMBL24864470 | 0.82 | SIRT1 (0.39) | FOLH1SIRT2SIRT1SIRT5CA1 | |
| SCHEMBL29342074 | 0.78 | KLKB1 (0.42) | FURINCA1CA2 | |
| SCHEMBL24864585 | 0.78 | FOLH1 (0.39) | FOLH1SIRT2SIRT1SIRT5 | |
| SCHEMBL24864394 | 0.78 | GLP1R (0.40) | FOLH1SIRT2SIRT1SIRT5CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280227-A2 | LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME | PROFOUNDBIO US CO. (US) | 2023-01-12 | — | — | WO | disclosed |