SCHEMBL24864395

CCC(=O)NCC(=O)N[C@H](C(=O)N[C@@H](CCCCNC(=O)CN(CCN(CC(=O)O)CC(=O)O)CC(=O)O)C(=O)Nc1ccc(CO)cc1)C(C)C

nearest known ligand 0.38

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	SIRT2	Q8IXJ6	7/20	0.38

▸	SIRT1	Q96EB6	7/20	0.38

▸	FURIN	P09958	2/20	0.38

▸	FOLH1	Q04609	1/20	0.37

▸	SIRT3	Q9NTG7	3/20	0.36

▸	SIRT5	Q9NXA8	2/20	0.36

▸	NPY1R	P25929	1/20	0.35

▸	CA1	P00915	2/20	0.34

▸	CA2	P00918	2/20	0.34

▸	CA12	O43570	1/20	0.34

▸	CA9	Q16790	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL24864633	0.93	QRFPR (0.38)	SIRT2SIRT1FURINFOLH1SIRT5
SCHEMBL24864619	0.90	FOLH1 (0.40)	SIRT2SIRT1FURINFOLH1SIRT3
SCHEMBL24864438	0.85	FOLH1 (0.39)	SIRT2SIRT1FURINFOLH1SIRT3
SCHEMBL27291574	0.85	FURIN (0.42)	SIRT2SIRT1FURINFOLH1SIRT3
SCHEMBL24864590	0.84	SIRT1 (0.40)	SIRT2SIRT1FOLH1SIRT3SIRT5
SCHEMBL24864470	0.83	SIRT1 (0.39)	SIRT2SIRT1FOLH1SIRT3SIRT5
SCHEMBL24864585	0.79	FOLH1 (0.39)	SIRT2SIRT1FOLH1SIRT3SIRT5
SCHEMBL24864394	0.79	GLP1R (0.40)	SIRT2SIRT1FOLH1SIRT5CA1
SCHEMBL27292223	0.78	FAP (0.41)	SIRT2SIRT1FURINFOLH1SIRT3
SCHEMBL23943639	0.77	FURIN (0.44)	SIRT2SIRT1FURINSIRT3NPY1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2023280227-A2	LINKERS, DRUG LINKERS AND CONJUGATES THEREOF AND METHODS OF USING THE SAME	PROFOUNDBIO US CO. (US)	2023-01-12	—	—	WO	disclosed