⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24340877 | 0.82 | — | — | |
| SCHEMBL22758126 | 0.77 | SMN1; SMN2 (0.39) | — | |
| SCHEMBL26047845 | 0.71 | — | — | |
| SCHEMBL12843875 | 0.71 | — | — | |
| SCHEMBL19594799 | 0.70 | LMNA (0.31) | — | |
| SCHEMBL25130841 | 0.70 | KDM4E (0.43) | — | |
| SCHEMBL20866434 | 0.70 | MAOA (0.34) | — | |
| SCHEMBL26259196 | 0.70 | — | — | |
| SCHEMBL23959148 | 0.69 | — | — | |
| SCHEMBL25064299 | 0.68 | SMN1; SMN2 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281480-A1 | CONJUGATES OF CHECKPOINT INHIBITORS WITH IL-2, AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-01-12 | — | — | WO | disclosed |