Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.57 |
| ▸ | PKM | P14618 | 4/20 | 0.57 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | TAS2R14 | Q9NYV8 | 3/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.57 |
| ▸ | TRIM24 | O15164 | 2/20 | 0.52 |
| ▸ | BRD1 | O95696 | 1/20 | 0.52 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30336350 | 1.00 | SMN1; SMN2 (0.57) | SMN1; SMN2PKMHTTTAS2R14TSHR | |
| SCHEMBL24865750 | 0.83 | HTT (0.46) | SMN1; SMN2PKMHTTTAS2R14TSHR | |
| SCHEMBL30336849 | 0.83 | HTT (0.46) | SMN1; SMN2PKMHTTTAS2R14TSHR | |
| SCHEMBL24777901 | 0.78 | ADRA2A (0.61) | SMN1; SMN2HTTTSHRMAPTALDH1A1 | |
| SCHEMBL24865481 | 0.75 | TRIM24 (0.61) | SMN1; SMN2PKMHTTTP53MAPT | |
| SCHEMBL1279478 | 0.73 | PKM (1.00) | SMN1; SMN2PKMHTTTAS2R14TSHR | |
| SCHEMBL24865728 | 0.72 | KDM4E (0.54) | SMN1; SMN2PKMHTTTP53HPGD | |
| SCHEMBL1616042 | 0.72 | TAS2R14 (1.00) | SMN1; SMN2PKMHTTTAS2R14TSHR | |
| SCHEMBL16923325 | 0.72 | RHOA (0.46) | SMN1; SMN2PKMHTTTSHRMAPT | |
| SCHEMBL24865206 | 0.72 | SMN1; SMN2 (0.53) | SMN1; SMN2PKMHTTTP53HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |