Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 3/20 | 0.40 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.40 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30885143 | 1.00 | GABRG2 (0.41) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL30336752 | 0.89 | GABRG2 (0.43) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL24865576 | 0.89 | GABRG2 (0.43) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL24865344 | 0.87 | CYP11B2 (0.44) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL24865333 | 0.86 | GABRG2 (0.41) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL30336183 | 0.86 | GABRG2 (0.41) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL31123240 | 0.86 | HTR1A (0.42) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL24865205 | 0.86 | HTR1A (0.42) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL24865497 | 0.85 | HTR1A (0.49) | GABRG2GABRB3GABRA5HTR1AHTR2C | |
| SCHEMBL24865535 | 0.84 | HTR1A (0.41) | GABRG2GABRB3GABRA5HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |