SCHEMBL2486562

SCHEMBL2486562

Cc1ccc(OCC(=O)c2cc(C(C)C)c(O)c(C(C)C)c2)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.49
HTT P42858 1/20 0.49
MAPT P10636 4/20 0.47
LMNA P02545 3/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
KDM4E B2RXH2 1/20 0.47
GABRA1 P14867 1/20 0.44
GABRB1 P18505 1/20 0.44
NPC1 O15118 1/20 0.43
TDP1 Q9NUW8 1/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
HPGD P15428 1/20 0.43
ALDH1A1 P00352 1/20 0.42
THRA P10827 1/20 0.41
THRB P10828 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13126936 0.76 MAPT (0.43) GAAHTTMAPTLMNAL3MBTL1
SCHEMBL13111339 0.74 GABRA1 (0.46) GAAHTTLMNAGABRA1GABRB1
SCHEMBL13674512 0.74 PTPN1 (0.53) GAAMAPTLMNAKDM4ENPC1
SCHEMBL8077322 0.73 GABRA1 (0.72) GAAHTTLMNAGABRA1GABRB1
SCHEMBL3732530 0.73 NPC1 (0.69) GAAMAPTLMNAL3MBTL1KDM4E
SCHEMBL11425674 0.72 MAPT (0.61) GAAHTTMAPTLMNAL3MBTL1
SCHEMBL27584559 0.71 GABRA1 (0.53) GAAHTTLMNAGABRA1GABRB1
SCHEMBL11847871 0.71 LMNA (0.64) GAAHTTMAPTLMNAL3MBTL1
SCHEMBL10757858 0.71 MAPT (0.57) MAPTLMNAL3MBTL1KDM4ENPC1
SCHEMBL6318934 0.71 MAPT (0.78) MAPTLMNAL3MBTL1KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1945705-B1 PHOTOLATENT SYSTEMS BASF SE (DE) 2011-10-19 EP disclosed
US-7820865-B2 Photolatent systems CIBA CORPORATION (US) 2010-10-26 US disclosed
US-7820865-B2 Photolatent systems CIBA CORPORATION (US) 2010-10-26 US disclosed
US-20090162307-A1 Photolatent Systems CIBA CORP. 2009-06-25 US disclosed
US-20090162307-A1 Photolatent Systems CIBA CORP. 2009-06-25 US disclosed
EP-1945705-A1 PHOTOLATENT SYSTEMS Ciba Holding Inc. (CH) 2008-07-23 EP disclosed
WO-2007054446-A1 PHOTOLATENT SYSTEMS CIBA HOLDING INC. (CH) 2007-05-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090162307-A1 Photolatent Systems CCNT1, CCNT2, C1S GAA 2162/4885HTT 150/4885MAPT 1104/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.