Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.78 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.78 |
| ▸ | LMNA | P02545 | 3/20 | 0.78 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.78 |
| ▸ | NPC1 | O15118 | 3/20 | 0.58 |
| ▸ | RAB9A | P51151 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | CPB1 | P15086 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325847 | 0.91 | MAPT (0.64) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL6321338 | 0.87 | MAPT (0.64) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL6202777 | 0.87 | MAPT (0.64) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL6328277 | 0.87 | MAPT (0.64) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL6319805 | 0.87 | MAPT (0.68) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL3868073 | 0.85 | MAPT (0.63) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL3866097 | 0.84 | MAPT (0.57) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL11847871 | 0.83 | LMNA (0.64) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL10757858 | 0.83 | MAPT (0.57) | MAPTL3MBTL1LMNAKDM4ENPC1 | |
| SCHEMBL6204121 | 0.83 | LMNA (0.64) | MAPTL3MBTL1LMNAKDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050272036-A1 | Ketones | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | US | disclosed |
| US-3993645-A | Stilbene optical brighteners and compositions brightened therewith | STERLING DRUG INC. (US) | 1976-11-23 | — | — | US | disclosed |
| US-3932301-A | NYLON, POLYESTERS | STERLING DRUG INC. (US) | 1976-01-13 | — | — | US | disclosed |