Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 1/20 | 0.37 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 3/20 | 0.34 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.32 |
| ▸ | WEE1 | P30291 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | BTK | Q06187 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865658 | 0.86 | SYK (0.34) | SYKKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24865300 | 0.82 | CNR2 (0.34) | KDM4EMAPT | |
| SCHEMBL24865791 | 0.74 | HRH3 (0.35) | SYKBTK | |
| SCHEMBL24865739 | 0.73 | ENPP2 (0.40) | MEN1ALDH1A1GAAMAPTKMT2A | |
| SCHEMBL24865601 | 0.72 | MEN1 (0.31) | MEN1ALDH1A1MAPTALOX15KMT2A | |
| SCHEMBL24865708 | 0.71 | MEN1 (0.33) | KDM4EMEN1ALDH1A1MAPTALOX15 | |
| SCHEMBL24865688 | 0.71 | EGFR (0.47) | KDM4EMEN1ALDH1A1GAAMAPT | |
| SCHEMBL24865767 | 0.68 | SYK (0.38) | SYKKDM4EMEN1ALDH1A1GAA | |
| SCHEMBL24865642 | 0.68 | BCL6 (0.47) | PDGFRBPDGFRAALDH1A1GAA | |
| SCHEMBL24865609 | 0.66 | MAPT (0.51) | KDM4EMEN1ALDH1A1GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |