Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 4/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.31 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865300 | 0.89 | CNR2 (0.34) | CNR2MAPTJAK2BRD4KDM4E | |
| SCHEMBL24865643 | 0.86 | PDGFRB (0.37) | SYKMAPTMAPK1MEN1KMT2A | |
| SCHEMBL24865791 | 0.81 | HRH3 (0.35) | SYKCNR2JAK2SMN1; SMN2BRD4 | |
| SCHEMBL24865770 | 0.76 | CNR2 (0.33) | CNR2JAK2HRH3 | |
| SCHEMBL24865467 | 0.74 | ALDH1A1 (0.33) | MAPTMAPK1TP53SMN1; SMN2MEN1 | |
| SCHEMBL24865637 | 0.74 | ALDH1A1 (0.33) | MAPTMAPK1TP53SMN1; SMN2MEN1 | |
| SCHEMBL24865739 | 0.74 | ENPP2 (0.40) | MAPTMEN1KMT2ATDP1GAA | |
| SCHEMBL24865601 | 0.72 | MEN1 (0.31) | MAPTMEN1KMT2ATDP1ALDH1A1 | |
| SCHEMBL24865708 | 0.72 | MEN1 (0.33) | MAPTMAPK1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL24865688 | 0.72 | EGFR (0.47) | MAPTMAPK1TP53SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |