Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865708 | 0.78 | MEN1 (0.33) | MEN1RGS12USP2ALDH1A1LMNA | |
| SCHEMBL24865688 | 0.78 | EGFR (0.47) | MEN1USP2ALDH1A1POLBMAPT | |
| SCHEMBL24865752 | 0.74 | PTK2 (0.38) | MEN1ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL24865739 | 0.73 | ENPP2 (0.40) | MEN1ALDH1A1LMNACYP1A2CYP2D6 | |
| SCHEMBL24865612 | 0.73 | PKM (0.38) | MEN1LMNACYP1A2CYP2D6MAPT | |
| SCHEMBL24865658 | 0.72 | SYK (0.34) | MEN1ALDH1A1MAPTALOX15KMT2A | |
| SCHEMBL24865643 | 0.72 | PDGFRB (0.37) | MEN1ALDH1A1MAPTALOX15KMT2A | |
| SCHEMBL24865300 | 0.69 | CNR2 (0.34) | MAPT | |
| SCHEMBL13136690 | 0.67 | HDAC8 (0.43) | ALDH1A1CYP1A2MAPTTHRBCYP2C9 | |
| SCHEMBL24865727 | 0.66 | MAPK1 (0.30) | MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |