⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29341946 | 0.84 | — | — | |
| SCHEMBL24878585 | 0.79 | CTSS (0.31) | — | |
| SCHEMBL24864722 | 0.79 | — | — | |
| SCHEMBL25130841 | 0.73 | KDM4E (0.43) | — | |
| SCHEMBL19594799 | 0.73 | LMNA (0.31) | — | |
| SCHEMBL23959148 | 0.72 | — | — | |
| SCHEMBL23958983 | 0.69 | MMP8 (0.31) | — | |
| SCHEMBL24774244 | 0.68 | HSD17B10 (0.37) | — | |
| SCHEMBL25030384 | 0.68 | — | — | |
| SCHEMBL7907381 | 0.67 | KDM4E (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281479-A1 | CHECKPOINT INHIBITORS CONJUGATED TO IL-2, AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-01-12 | — | — | WO | disclosed |