⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865647 | 0.79 | — | — | |
| SCHEMBL21507374 | 0.72 | MEN1 (0.33) | — | |
| SCHEMBL18459795 | 0.70 | — | — | |
| SCHEMBL21507446 | 0.67 | ENPEP (0.41) | — | |
| SCHEMBL3665094 | 0.66 | TNF (0.35) | — | |
| SCHEMBL29341946 | 0.65 | — | — | |
| SCHEMBL24340893 | 0.65 | MGLL (0.32) | — | |
| SCHEMBL20071792 | 0.64 | REN (0.36) | — | |
| SCHEMBL20072154 | 0.64 | FFAR2 (0.30) | — | |
| SCHEMBL25130841 | 0.64 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023281480-A1 | CONJUGATES OF CHECKPOINT INHIBITORS WITH IL-2, AND USES THEREOF | BRIGHT PEAK THERAPEUTICS AG (CH) | 2023-01-12 | — | — | WO | disclosed |