Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | BCL6 | P41182 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 3/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.31 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865707 | 0.90 | JAK2 (0.32) | ALKBCL6F10JAK2BRD4 | |
| SCHEMBL24865544 | 0.79 | BCL6 (0.35) | ALKBCL6F10JAK2BRD4 | |
| SCHEMBL24865215 | 0.79 | PTK2 (0.33) | ALKBCL6CHRM4F10JAK2 | |
| SCHEMBL24864955 | 0.79 | KDM4E (0.36) | ALKBCL6JAK2BRD4KDM4E | |
| SCHEMBL24865645 | 0.77 | FGFR3 (0.34) | BCL6 | |
| SCHEMBL24865437 | 0.76 | BCL6 (0.38) | BCL6KDM4EMAPTACACB | |
| SCHEMBL24865761 | 0.74 | JAK2 (0.33) | BCL6JAK2KDM4EMAPTLRRK2 | |
| SCHEMBL24865335 | 0.73 | KIT (0.35) | BCL6KDM4EMAPTACACB | |
| SCHEMBL24865469 | 0.70 | MAPT (0.34) | BCL6JAK2KDM4EMAPT | |
| SCHEMBL30336317 | 0.67 | HTR1A (0.37) | F10JAK2LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |