Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 2/20 | 0.32 |
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865667 | 0.90 | ALK (0.33) | JAK2BRD4ALKBCL6F10 | |
| SCHEMBL24865544 | 0.79 | BCL6 (0.35) | JAK2BRD4ALKBCL6F10 | |
| SCHEMBL24865215 | 0.79 | PTK2 (0.33) | JAK2ALKBCL6F10 | |
| SCHEMBL24864955 | 0.79 | KDM4E (0.36) | JAK2BRD4ALKBCL6 | |
| SCHEMBL24865645 | 0.77 | FGFR3 (0.34) | BCL6 | |
| SCHEMBL24865437 | 0.76 | BCL6 (0.38) | BCL6 | |
| SCHEMBL24865761 | 0.74 | JAK2 (0.33) | JAK2BCL6 | |
| SCHEMBL24865335 | 0.73 | KIT (0.35) | BCL6 | |
| SCHEMBL24865650 | 0.70 | CNR2 (0.34) | BCL6 | |
| SCHEMBL25193242 | 0.70 | L3MBTL1 (0.40) | ALK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |