Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.33 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.32 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR6 | P50406 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | JAK1 | P23458 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865762 | 0.85 | NPC1 (0.33) | EGFRERBB3MAPK9MAPK10NPC1 | |
| SCHEMBL24865741 | 0.81 | CNR2 (0.34) | EGFRERBB3MAPK9MAPK10NPC1 | |
| SCHEMBL24865611 | 0.79 | BRD4 (0.33) | EGFRERBB3MAPK9MAPK10NPC1 | |
| SCHEMBL24865760 | 0.73 | SMN1; SMN2 (0.43) | BRD4 | |
| SCHEMBL24865793 | 0.71 | ALDH1A1 (0.41) | MEN1KMT2A | |
| SCHEMBL31123346 | 0.71 | ALDH1A1 (0.35) | CNR2HTR1AJAK1MEN1KMT2A | |
| SCHEMBL24865689 | 0.71 | ALDH1A1 (0.35) | CNR2HTR1AJAK1MEN1KMT2A | |
| SCHEMBL31123292 | 0.70 | KIF11 (0.53) | HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL29209076 | 0.70 | KIF11 (0.53) | HTR1AHTR2AMEN1KMT2A | |
| SCHEMBL31123243 | 0.69 | ALOX5 (0.42) | HTR1AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |