Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | BCL6 | P41182 | 1/20 | 0.31 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.31 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.31 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | HTR1D | P28221 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24865690 | 0.86 | OPRK1 (0.35) | CNR2MAPTMEN1LMNAKMT2A | |
| SCHEMBL24865771 | 0.85 | MAPK13 (0.33) | CNR2MAPTEGFRKDM4EBCL6 | |
| SCHEMBL24865692 | 0.81 | EGFR (0.33) | CNR2EGFRERBB3MEN1KMT2A | |
| SCHEMBL24865300 | 0.80 | CNR2 (0.34) | CNR2HRH3MAPTKDM4EBCL6 | |
| SCHEMBL24865745 | 0.78 | MAPK10 (0.44) | EGFRMAPK10MAPK9MAPK8 | |
| SCHEMBL24865544 | 0.78 | BCL6 (0.35) | CNR2HRH3MAPTEGFRKDM4E | |
| SCHEMBL24865716 | 0.77 | HRH3 (0.35) | CNR2HRH3MAPTMEN1LMNA | |
| SCHEMBL24865618 | 0.75 | CNR2 (0.36) | CNR2HRH3MAPTMEN1LMNA | |
| SCHEMBL24865620 | 0.75 | DRD2 (0.38) | CNR2MAPTMEN1KMT2AKDM4E | |
| SCHEMBL30885112 | 0.75 | CNR2 (0.36) | CNR2HRH3MAPTMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280296-A1 | FERROPTOSIS MODULATORS, PREPARATIONS, AND USES THEREOF | Sironax Ltd. (KY) | 2023-01-12 | — | — | WO | disclosed |