Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 8/20 | 0.39 |
| ▸ | KDR | P35968 | 8/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867209 | 0.84 | ACACB (0.41) | — | |
| SCHEMBL24867304 | 0.82 | RAB9A (0.40) | RAB9APTGS1PTGS2AURKAALDH1A1 | |
| SCHEMBL24867298 | 0.82 | PTGS1 (0.38) | RAB9APTGS1PTGS2AURKA | |
| SCHEMBL24867214 | 0.81 | RAB9A (0.43) | RAB9ACYP2C9PTGS1PTGS2SMN1; SMN2 | |
| SCHEMBL24867297 | 0.81 | PTGS1 (0.45) | RAB9ANPC1PTGS1PTGS2AURKA | |
| SCHEMBL24867187 | 0.80 | ACACB (0.38) | CDK1RAB9APTGS1PTGS2AURKA | |
| SCHEMBL24867215 | 0.79 | PTGS1 (0.41) | CDK1KDRRAB9APTGS1PTGS2 | |
| SCHEMBL24866867 | 0.78 | PTGS1 (0.36) | RAB9APTGS1PTGS2 | |
| SCHEMBL24867148 | 0.76 | RAB9A (0.40) | RAB9ANPC1CYP2C9PTGS1PTGS2 | |
| SCHEMBL24866885 | 0.75 | RAB9A (0.52) | RAB9ACYP1A2CYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |