Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 3/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 5/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 3/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | ACACB | O00763 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866934 | 0.88 | GRM5 (0.43) | VNN1RORCRAB9A | |
| SCHEMBL24866886 | 0.88 | HDAC3 (0.41) | VNN1RORCHDAC3HDAC1HDAC2 | |
| SCHEMBL24866925 | 0.87 | VNN1 (0.46) | VNN1RORCHDAC3HDAC1HDAC2 | |
| SCHEMBL24866949 | 0.86 | VNN1 (0.41) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24867208 | 0.85 | HDAC3 (0.41) | VNN1RORCHDAC3HDAC1HDAC2 | |
| SCHEMBL24867489 | 0.85 | CDK2 (0.38) | HDAC3HDAC1HDAC2HDAC6RAB9A | |
| SCHEMBL24867486 | 0.85 | RAB9A (0.44) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24866927 | 0.84 | AURKA (0.38) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24866939 | 0.84 | VNN1 (0.41) | VNN1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL24867202 | 0.81 | VNN1 (0.50) | VNN1RAB9AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |