Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.37 |
| ▸ | ACACB | O00763 | 5/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CCNK | O75909 | 1/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.35 |
| ▸ | IGF1R | P08069 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24867184 | 0.89 | GRM5 (0.38) | CDK2RAB9ASYK | |
| SCHEMBL24867186 | 0.87 | KDM4C (0.37) | KDM4C | |
| SCHEMBL24866928 | 0.85 | VNN1 (0.46) | RAB9AACACBMAPK1HDAC3HDAC1 | |
| SCHEMBL24866886 | 0.84 | HDAC3 (0.41) | RAB9AACACBMAPK1HDAC3HDAC1 | |
| SCHEMBL24866925 | 0.83 | VNN1 (0.46) | CDK2RAB9AACACBMAPK1HDAC3 | |
| SCHEMBL24867490 | 0.82 | ACACB (0.43) | ACACBSYK | |
| SCHEMBL24866869 | 0.82 | PDE4A (0.42) | RAB9AACACBHDAC3HDAC1HDAC6 | |
| SCHEMBL24867208 | 0.82 | HDAC3 (0.41) | RAB9AACACBMAPK1HDAC3HDAC1 | |
| SCHEMBL24867486 | 0.81 | RAB9A (0.44) | RAB9AACACBMAPK1HDAC3HDAC1 | |
| SCHEMBL24866867 | 0.80 | PTGS1 (0.36) | RAB9ATBK1ACACBMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |