Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 7/20 | 0.47 |
| ▸ | IDH1 | O75874 | 4/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24866902 | 0.84 | HDAC3 (0.46) | SYKKDR | |
| SCHEMBL24866909 | 0.83 | AKT1 (0.42) | SYKPTGS1 | |
| SCHEMBL24867231 | 0.83 | CFD (0.39) | SYK | |
| SCHEMBL24867228 | 0.81 | AKT1 (0.46) | SYKKDR | |
| SCHEMBL24867233 | 0.81 | CDK2 (0.43) | SYK | |
| SCHEMBL24866903 | 0.78 | CDK5 (0.40) | SYK | |
| SCHEMBL24867225 | 0.75 | PTGS1 (0.43) | SYKTBXA2RPTGS1 | |
| SCHEMBL8181222 | 0.73 | LOXL2 (0.61) | — | |
| SCHEMBL26115849 | 0.73 | RAPGEF4 (0.43) | ADORA1 | |
| SCHEMBL24866862 | 0.72 | HDAC3 (0.48) | PTGS1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283488-A9 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CZ BIOHUB SF, LLC (US) | 2023-05-25 | — | — | WO | disclosed |
| WO-2023283488-A2 | CDK19-SELECTIVE INHIBITORS, AND METHODS OF USE THEREOF | CHAN ZUCKERBERG BIOHUB, INC. (US) | 2023-01-12 | — | — | WO | disclosed |