SCHEMBL248682

SCHEMBL248682

Nc1ccn(Cc2ccccc2)c(=O)n1

nearest known ligand 0.49

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 6/20 0.49
ADORA2A P29274 1/20 0.49
MAPK14 Q16539 5/20 0.45
KMT2A Q03164 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HPGD P15428 2/20 0.44
PKM P14618 1/20 0.44
HSD17B10 Q99714 1/20 0.44
HTT P42858 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
TP53 P04637 1/20 0.44
CYP2D6 P10635 1/20 0.44
PNP P00491 2/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22631571 0.87 EP300 (0.44) EP300ADORA2AKMT2AKDM4EALDH1A1
SCHEMBL21977355 0.83 MAPT (0.49) EP300MAPK14KMT2AALDH1A1SMN1; SMN2
SCHEMBL17554285 0.83 EP300 (0.44) EP300ADORA2AKMT2AALDH1A1HTT
SCHEMBL27549707 0.80 EP300 (0.42) EP300KMT2ACYP2D6
SCHEMBL28888847 0.80 EP300 (0.45) EP300KMT2ASMN1; SMN2CYP2D6
SCHEMBL2035525 0.80 F2R (0.48) EP300KMT2ACYP2D6MEN1
SCHEMBL2383961 0.79 FGFR1 (0.39) EP300KMT2AALDH1A1CYP2D6MEN1
SCHEMBL2341203 0.78 MPO (0.41) EP300KMT2AKDM4EALDH1A1HPGD
SCHEMBL5265127 0.78 MAPK14 (0.58) ADORA2AMAPK14KMT2AALDH1A1HPGD
SCHEMBL16446911 0.77 FGFR1 (0.47) EP300CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 820 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4746918-A1 METHODS OF PREPARING SURFACE MODIFIED VIRAL CAPSIDS Borea Therapeutics S.r.l. (IT) 2026-05-27 EP claimed
WO-2026102435-A1 METHODS OF NUCLEIC ACID PROCESSING AND SYNTHESIS UNIVERSITY OF MASSACHUSETTS (US) 2026-05-15 WO claimed
WO-2026101423-A1 PHOTOSWITCHABLE CHEMICAL INDUCED DIMERIZATION SYSTEMS FOR CONTROL OF CELLULAR ACTIVITIES WITH LIGHT WU YAOWEN (SE) 2026-05-15 WO claimed
WO-2026085618-A1 METHOD OF IMMOBILIZING CAPTURE PROBES TO SOLID PHASES FOR TARGET SUBSTANCE DETECTION YYZ PHARMATECH INC. (CA) 2026-04-30 WO claimed
EP-4716533-A2 FLUORESCENT INDICATORS FOR METAL ION DETECTION AS SUBSTRATES FOR A SELF-LABELING ENZYME Ion Biosciences (US) 2026-04-01 EP claimed
US-12560608-B2 Detection of molecular associations CALIFORNIA INSTITUTE OF TECHNOLOGY (US) 2026-02-24 US claimed
EP-4688872-A1 CLICK-TO-INSTALL GENOME EDITING The General Hospital Corporation (US) 2026-02-11 EP claimed
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE FREISTAAT BAYERN LUDWIG MAXIMILIANS UNIV MUENCHEN (DE) 2025-12-11 US claimed
US-20250333696-A1 DNA-CHIMERIC ANTIGEN RECEPTOR T CELLS FOR IMMUNOTHERAPY UNIV ARIZONA STATE (US) 2025-10-30 US claimed
US-20250326723-A1 Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly UNIV NORTHWESTERN (US) 2025-10-23 US claimed
WO-2010046067-A1 IMPROVED ALLELE-SPECIFIC AMPLIFICATION ROCHE DIAGNOSTICS GMBH (DE) 2010-04-29 WO claimed
US-20100099110-A1 Allele-Specific Amplification ROCHE MOLECULAR SYSTEMS, INC. (US) 2010-04-22 US claimed
WO-2010012962-A2 METHOD FOR DETECTING MEMBRANE PROTEIN INTERNALIZATION CIS-BIO INTERNATIONAL (FR) 2010-02-04 WO claimed
WO-2009060065-A1 METHOD OF QUANTIFYING TRANSIENT INTERACTIONS BETWEEN PROTEINS COVALYS BIOSCIENCES AG (CH) 2009-05-14 WO claimed
EP-2049499-A1 LABELLING OF FUSION PROTEINS WITH SYNTHETIC PROBES EPFL Ecole Polytechnique Fédérale de Lausanne (CH) 2009-04-22 EP claimed
EP-1895840-A2 P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES Inspire Pharmaceuticals, Inc. (US) 2008-03-12 EP claimed
WO-2008012296-A1 LABELLING OF FUSION PROTEINS WITH SYNTHETIC PROBES EPFL - ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (CH) 2008-01-31 WO claimed
EP-1882688-A1 Labelling of fusion proteins with synthetic probes EPFL Ecole Polytechnique Fédérale de Lausanne (CH) 2008-01-30 EP claimed
US-20070015726-A1 P2Y6 receptor agonists for treating lung diseases MERCK SHARP & DOHME LLC 2007-01-18 US claimed
WO-2007002945-A2 P2Y6 RECEPTOR AGONISTS FOR TREATING LUNG DISEASES INSPIRE PHARMACEUTICALS, INC. (US) 2007-01-04 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070015726-A1 P2Y6 receptor agonists for treating lung diseases P2RY6, P2RY1, P2RY11 EP300 3997/4885ADORA2A 22/4885MAPK14 4362/4885
US-20250377301-A1 STABILISED FLUOROPHORES, COMPOSITIONS, METHODS OF PREPARATION, CONJUGATES THEREOF, AND METHODS OF USE CRY1, MKI67, IK EP300 4874/4885ADORA2A 384/4885MAPK14 2867/4885
US-12560608-B2 Detection of molecular associations APP, SPPL2A, SPPL2B EP300 3019/4885ADORA2A 3529/4885MAPK14 2894/4885
US-20100099110-A1 Allele-Specific Amplification RNGTT, HLA-C, POLL EP300 4461/4885ADORA2A 354/4885MAPK14 4068/4885
US-20250326723-A1 Development of an Enzyme-Inhibitor Reaction Using Cellular Retinoic Acid Binding Protein II for One-Pot Megamolecule Assembly CRABP2, RARB, RARA EP300 4033/4885ADORA2A 3325/4885MAPK14 4112/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.