Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | SPR | P35270 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19657271 | 0.88 | HPGD (0.46) | KMT2AALDH1A1SMN1; SMN2HPGDTSHR | |
| SCHEMBL24869257 | 0.87 | SPR (0.40) | HPGDSPR | |
| SCHEMBL24869247 | 0.80 | HCRTR1 (0.37) | KMT2AALDH1A1MEN1LMNATSHR | |
| SCHEMBL24869567 | 0.80 | ALDH1A1 (0.40) | KMT2AALDH1A1MEN1LMNASMN1; SMN2 | |
| SCHEMBL24869264 | 0.79 | KDM5A (0.34) | ALDH1A1MALT1TSHRSPR | |
| SCHEMBL4259443 | 0.79 | SPR (0.50) | KMT2AMEN1HPGDPOLBTSHR | |
| SCHEMBL18839478 | 0.78 | HSD11B1 (0.50) | KMT2AALDH1A1MALT1HPGDPOLB | |
| SCHEMBL24869265 | 0.77 | SPR (0.38) | SPRADORA2A | |
| SCHEMBL4255887 | 0.77 | SPR (0.51) | KMT2AMEN1SMN1; SMN2MALT1HPGD | |
| SCHEMBL14303040 | 0.77 | HSD11B1 (0.53) | KMT2AALDH1A1HPGDPOLBTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |