Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPR | P35270 | 3/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 13/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869257 | 0.87 | SPR (0.40) | SPRP2RX7 | |
| SCHEMBL24868721 | 0.84 | SPR (0.37) | SPRADRA1A | |
| SCHEMBL24869264 | 0.83 | KDM5A (0.34) | SPR | |
| SCHEMBL24869248 | 0.78 | P2RX7 (0.36) | P2RX7 | |
| SCHEMBL24869249 | 0.77 | KMT2A (0.47) | SPRADORA2A | |
| SCHEMBL24869247 | 0.77 | HCRTR1 (0.37) | — | |
| SCHEMBL19657271 | 0.74 | HPGD (0.46) | — | |
| SCHEMBL24869656 | 0.66 | CHRNB2 (0.44) | SPRADRA1A | |
| SCHEMBL18711718 | 0.65 | EPHX2 (0.45) | SPRADRA1A | |
| SCHEMBL12546067 | 0.63 | TSHR (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |