Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.34 |
| ▸ | ACACB | O00763 | 3/20 | 0.33 |
| ▸ | PHGDH | O43175 | 2/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.32 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.32 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16248222 | 0.75 | P2RY12 (0.40) | P2RY12TRPV1 | |
| SCHEMBL14349216 | 0.74 | P2RY12 (0.39) | P2RY12TRPV1 | |
| SCHEMBL24869248 | 0.72 | P2RX7 (0.36) | HRH4HRH3KCNH2P2RY12ACACB | |
| SCHEMBL15599194 | 0.71 | CHRNB2 (0.47) | HRH4 | |
| SCHEMBL12891545 | 0.71 | GRM4 (0.41) | P2RY12 | |
| SCHEMBL21470275 | 0.71 | LMNA (0.47) | — | |
| SCHEMBL24869545 | 0.71 | HRH4 (0.33) | HRH4HRH3KCNH2P2RY12CXCR3 | |
| SCHEMBL21030633 | 0.68 | MALT1 (0.44) | — | |
| SCHEMBL24869254 | 0.68 | GLP1R (0.46) | P2RY12TRPV1 | |
| SCHEMBL17244900 | 0.68 | P2RX7 (0.37) | HRH4HRH3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |