Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 11/20 | 0.36 |
| ▸ | MAP3K12 | Q12852 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ACACB | O00763 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24869214 | 0.82 | MAP3K12 (0.38) | MAP3K12HRH3POLB | |
| SCHEMBL24869265 | 0.78 | SPR (0.38) | P2RX7 | |
| SCHEMBL16248222 | 0.74 | P2RY12 (0.40) | POLBP2RY12 | |
| SCHEMBL14349216 | 0.73 | P2RY12 (0.39) | POLBP2RY12 | |
| SCHEMBL24869253 | 0.72 | HRH4 (0.36) | HRH4HRH3KCNH2ACACBP2RY12 | |
| SCHEMBL15599194 | 0.71 | CHRNB2 (0.47) | HRH4 | |
| SCHEMBL12891545 | 0.71 | GRM4 (0.41) | POLBP2RY12 | |
| SCHEMBL24869545 | 0.70 | HRH4 (0.33) | HRH4HRH3KCNH2P2RY12 | |
| SCHEMBL21470275 | 0.68 | LMNA (0.47) | POLB | |
| SCHEMBL24869257 | 0.68 | SPR (0.40) | P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023279986-A1 | SIX-MEMBERED ARYL OR HETEROARYL AMIDES, AND COMPOSITION AND USE THEREOF | 贝达药业股份有限公司 | 2023-01-12 | — | — | WO | disclosed |