Sugi Predict

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Carbon Tetrachloride

Carbon Tetrachloride

SCHEMBL313349

ClC(Cl)(Cl)Cl.c1ccc(P(c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.75

Full drug profile on Sugi Atlas →

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ CYP3A4 P08684 1/20 0.75
▸ TDP1 Q9NUW8 1/20 0.75
▸ ESR1 P03372 4/20 0.55
▸ ESR2 Q92731 4/20 0.55
▸ TSHR P16473 5/20 0.43
▸ KDM4E B2RXH2 1/20 0.42
▸ GAA P10253 1/20 0.42
▸ CYP1A2 P05177 1/20 0.35
▸ NPSR1 Q6W5P4 1/20 0.33
▸ DRD1 P21728 2/20 0.32
▸ ALDH1A1 P00352 2/20 0.32
▸ BBOX1 O75936 1/20 0.30
▸ EHMT2 Q96KQ7 1/20 0.30
▸ EHMT1 Q9H9B1 1/20 0.30
▸ KCNN4 O15554 1/20 0.30
▸ LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11728684 0.91 TDP1 (0.71) CYP3A4TDP1ESR1ESR2TSHR
Hexachloroethane SCHEMBL2865671 0.91 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2TSHR
Chloromethane SCHEMBL248726 0.90 CYP3A4 (0.80) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL480830 0.90 TDP1 (0.92) CYP3A4TDP1ESR1ESR2TSHR
Chloromethane SCHEMBL6903208 0.88 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL561726 0.87 TDP1 (0.86) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL1951204 0.87 TDP1 (0.86) CYP3A4TDP1ESR1ESR2TSHR
SCHEMBL9420677 0.87 TDP1 (0.86) CYP3A4TDP1ESR1ESR2TSHR
Hydrochloric Acid SCHEMBL10793314 0.87 TDP1 (0.86) CYP3A4TDP1ESR1ESR2TSHR
Hydrochloric Acid SCHEMBL6374031 0.87 TDP1 (0.86) CYP3A4TDP1ESR1ESR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 476 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115974782-A Photoaffinity probe for isoburenic acid, and preparation method and application thereof 南京科络思生物科技有限公司 2023-04-18 — — CN claimed
CN-108689903-B Novel preparation method of brivaracetam 北京艾百诺医药股份有限公司 2019-12-24 — — CN claimed
EP-1268461-B1 PROCESS FOR THE PREPARATION OF CITALOPRAM RESOLUTION CHEMICALS LTD (GB) 2006-03-15 — — EP claimed
US-7002025-B2 Process for the preparation of citalopram RESOLUTION CHEMICALS LIMITED (GB) 2006-02-21 — — US claimed
US-20040014997-A1 Process for the preparation of citalopram RESOLUTION CHEMICALS LIMITED (GB) 2004-01-22 — — US claimed
US-5468719-A N-acyl-n-phenyltetrahydrophthalamic acid derivatives, methods of producing same, and herbicides containing same as effective components CENTRAL GLASS COMPANY, LIMITED (JP) 1995-11-21 — — US claimed
EP-0600089-A1 N-ACYL-N-PHENYLTETRAHYDROPHTHALAMIC ACID DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT CENTRAL GLASS COMPANY, LIMITED (JP) 1994-06-08 — — EP claimed
EP-0496900-A1 N-ACYL-N-PHENYLTETRAHYDROPHTHALAMIC ACID DERIVATIVE, PRODUCTION THEREOF, AND HERBICIDE CONTAINING THE SAME AS ACTIVE INGREDIENT CENTRAL GLASS COMPANY, LIMITED (JP) 1992-08-05 — — EP claimed
EP-0333445-A2 Aromatic allene compounds and preparation thereof NIPPON PAINT CO., LTD. (JP) 1989-09-20 — — EP claimed
EP-0137717-A2 Fungicidal triazole and imidazole compounds E.I. DU PONT DE NEMOURS AND COMPANY (US) 1985-04-17 — — EP claimed
EP-0015140-B1 THERMOLYSIS OF 2-(3-ARYL-ISOXAZOL-5-YL)BENZOIC ACIDS, SALTS AND HALIDES FROM 3'-(ARYL)-SPIRO(ISOBENZOFURAN-1(3H),5'(4'H)ISOXAZOL)-3-ONES MONSANTO COMPANY (US) 1983-12-14 — — EP claimed
US-4223154-A Preparation of 2-(3-aryl-5-isoxazol) benzoyl halide MONSANTO COMPANY (US) 1980-09-16 — — US claimed
EP-0015140-A1 Thermolysis of 2-(3-aryl-isoxazol-5-yl)benzoic acids, salts and halides from 3'-(aryl)-spiro(isobenzofuran-1(3H),5'(4'H)isoxazol)-3-ones MONSANTO COMPANY (US) 1980-09-03 — — EP claimed
JP-1233253-A — — None — — JP disclosed
JP-62286958-A — — None — — JP disclosed
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES Atea Pharmaceuticals, Inc. (US) 2023-10-19 — — US disclosed
US-4239709-A CYCLIZING AN AMINOALCOHOL WITH A PHOSPHORUS OXYHALIDE, THESE CYCLOPHOSPHAMIDE DERIVATIVES ARE USEFUL AGAINST LEUKEMIA OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1980-12-16 — — US disclosed
US-4223154-A Preparation of 2-(3-aryl-5-isoxazol) benzoyl halide MONSANTO COMPANY (US) 1980-09-16 — — US disclosed
EP-0015140-A1 Thermolysis of 2-(3-aryl-isoxazol-5-yl)benzoic acids, salts and halides from 3'-(aryl)-spiro(isobenzofuran-1(3H),5'(4'H)isoxazol)-3-ones MONSANTO COMPANY (US) 1980-09-03 — — EP disclosed
US-4091226-A Novel cyclopentenecarboxylates ROUSSEL UCLAF (FR) 1978-05-23 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040014997-A1 Process for the preparation of citalopram MAOB, TPH1, TPH2 CYP3A4 88/4885TDP1 2755/4885ESR1 3418/4885
US-20230331751-A1 STEREOSELECTIVE MANUFACTURE OF SELECTED PURINE PHOSPHORAMIDATES NUDT1, PNP, ATIC CYP3A4 1370/4885TDP1 523/4885ESR1 4658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.