⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31289309 | 0.98 | L3MBTL1 (0.56) | — | |
| Hydrogen Sulfide SCHEMBL28157136 | 0.98 | L3MBTL1 (0.56) | — | |
| Hydrochloric Acid SCHEMBL9794067 | 0.98 | L3MBTL1 (0.56) | — | |
| Fluoromethane SCHEMBL27694445 | 0.96 | L3MBTL1 (0.55) | — | |
| SCHEMBL28147463 | 0.84 | VNN1 (0.49) | — | |
| Niacin SCHEMBL28333191 | 0.83 | ALDH1A1 (0.66) | — | |
| SCHEMBL17007892 | 0.83 | GRN (0.46) | — | |
| SCHEMBL334868 | 0.82 | — | — | |
| SCHEMBL1222255 | 0.81 | CHEK1 (0.70) | — | |
| SCHEMBL368970 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1369 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380932-B1 | PROCESS FOR PREPARING AFICAMTEN | CYTOKINETICS INC (US) | 2025-11-26 | — | — | EP | claimed |
| CN-119504588-A | Preparation method of fluorine-containing pyrazole derivative | 多氟多新材料股份有限公司 | 2025-02-25 | — | — | CN | claimed |
| CN-119221048-A | Anti-warping additive, electrolytic copper foil bath solution, copper foil, preparation method and application thereof | 吉和昌新材料(荆门)有限公司 | 2024-12-31 | — | — | CN | claimed |
| CN-110167944-B | Substituted pyrazoloazepin-4-ones and their use as phosphodiesterase inhibitors | 联合疗法公司 | 2024-08-23 | — | — | CN | claimed |
| US-12065436-B2 | Cardiac sarcomere inhibitors | CYTOKINETICS, INC. (US) | 2024-08-20 | — | — | US | claimed |
| EP-4380932-A1 | PROCESS FOR PREPARING AFICAMTEN | Cytokinetics, Inc. (US) | 2024-06-12 | — | — | EP | claimed |
| CN-117813304-A | Method for preparing alfukanitai | 赛特凯恩蒂克公司 | 2024-04-02 | — | — | CN | claimed |
| US-11932631-B2 | Process for preparing aficamten | CYTOKINETICS, INC. (US) | 2024-03-19 | — | — | US | claimed |
| CN-114105766-B | Preparation method of fluoro acyl fluoride | 科莱博(江苏)科技股份有限公司 | 2024-02-27 | — | — | CN | claimed |
| CN-117603140-A | Pyrazole acyl urea or thiourea compound containing substituted biphenyl structure, and preparation method and application thereof | 浙江树人学院 | 2024-02-27 | — | — | CN | claimed |
| US-20070032478-A1 | Kinase Inhibitors | ALLERGAN, INC. | 2007-02-08 | — | — | US | claimed |
| WO-2007008895-A1 | KINASE INHIBITORS | ALLERGAN, INC. (US) | 2007-01-18 | — | — | WO | claimed |
| US-7135475-B2 | Antidiabetic agents | HOFFMANN-LA ROCHE INC. (US) | 2006-11-14 | — | — | US | claimed |
| EP-1636223-A1 | BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. Hoffman-la Roche AG (CH) | 2006-03-22 | — | — | EP | claimed |
| WO-2005000842-A1 | BENZOTHIAZOLE DERIVATIVES AS ADENOSINE RECEPTOR LIGANDS | F. HOFFMAN-LA ROCHE AG (CH) | 2005-01-06 | — | — | WO | claimed |
| US-20040235915-A1 | Benzothiazole derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 2004-11-25 | — | — | US | claimed |
| US-20040014766-A1 | Amide substituted xanthine derivatives | HOFFMANN-LA ROCHE INC. | 2004-01-22 | — | — | US | claimed |
| CN-1298644-A | Herbiciding effervescent tablet for paddy rice | CHEN FENGXI (CN) | 2001-06-13 | — | — | CN | claimed |
| EP-0350176-B1 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL IND LTD (JP) | 1995-08-30 | — | — | EP | claimed |
| EP-0350176-A2 | Method for preparing pyrazolecarboxylic acid and derivatives | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1990-01-10 | — | — | EP | claimed |