Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VNN1 | O95497 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | GRN | P28799 | 1/20 | 0.46 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.44 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.44 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | DHX9 | Q08211 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.38 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702311 | 0.88 | ALDH1A1 (0.52) | VNN1SMN1; SMN2GRNSORT1RAB9A | |
| SCHEMBL334868 | 0.84 | — | — | |
| SCHEMBL248730 | 0.84 | — | — | |
| SCHEMBL20151710 | 0.82 | VNN1 (0.61) | VNN1SMN1; SMN2RAB9ALMNAALDH1A1 | |
| SCHEMBL31289309 | 0.82 | L3MBTL1 (0.56) | SMN1; SMN2GRNSORT1RAB9ALMNA | |
| SCHEMBL368970 | 0.82 | — | — | |
| Hydrogen Sulfide SCHEMBL28157136 | 0.82 | L3MBTL1 (0.56) | SMN1; SMN2GRNSORT1RAB9ALMNA | |
| Hydrochloric Acid SCHEMBL9794067 | 0.82 | L3MBTL1 (0.56) | SMN1; SMN2GRNSORT1RAB9ALMNA | |
| SCHEMBL872178 | 0.82 | — | — | |
| SCHEMBL20151747 | 0.81 | LMNA (0.40) | VNN1SMN1; SMN2GRNSORT1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4553076-A1 | COMPOUNDS AS TRK INHIBITORS AND/OR RET INHIBITORS AND USE THEREOF | Medinno Pharmaceutical Technology (Zhuhai) Co., Ltd. (CN) | 2025-05-14 | — | — | EP | disclosed |
| CN-106604917-A | Novel dihydroquinoline pyrazolyl compounds as aldosterone synthase inhibitors | 豪夫迈·罗氏有限公司 | 2017-04-26 | — | — | CN | disclosed |