Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 5/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8385048 | 0.78 | TSHR (0.49) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL19921260 | 0.78 | ACHE (0.47) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL5245719 | 0.78 | — | — | |
| SCHEMBL29764656 | 0.78 | TSHR (0.38) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL25941802 | 0.78 | TSHR (0.38) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL12846318 | 0.77 | CA12 (0.41) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL18131109 | 0.77 | LMNA (0.44) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL1415901 | 0.77 | TSHR (0.40) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL12787080 | 0.77 | CHRNB2 (0.44) | LMNATSHRNFKB1TDP1CYP3A4 | |
| SCHEMBL12835742 | 0.76 | ADRB2 (0.41) | LMNANFKB1TDP1ADRA1ACHRNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023283453-A1 | PHENYL ACETAMIDE BASED IL-17A MODULATORS AND USES THEREOF | DICE ALPHA, INC. (US) | 2023-01-12 | — | — | WO | disclosed |