Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 6/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876183 | 0.89 | MEN1 (0.38) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL30210923 | 0.79 | FFAR4 (0.47) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL24876323 | 0.76 | MAPT (0.36) | MAPTEPHX2EPHX1CCNA2CDK2 | |
| SCHEMBL30210899 | 0.67 | ATM (0.42) | MAPTMEN1KMT2ATP53SMN1; SMN2 | |
| SCHEMBL203169 | 0.67 | MAPT (0.53) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL14322739 | 0.67 | MAPT (0.58) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL24876247 | 0.66 | FFAR4 (0.51) | MAPTTP53SMN1; SMN2FFAR4ALDH1A1 | |
| SCHEMBL31236109 | 0.66 | FFAR4 (0.51) | MAPTTP53SMN1; SMN2FFAR4ALDH1A1 | |
| SCHEMBL24876191 | 0.66 | MAPT (0.45) | MAPTMEN1KMT2AHTTTP53 | |
| SCHEMBL20529653 | 0.66 | MAPT (0.49) | MAPTMEN1KMT2AHTTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |