Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.35 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 8/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.34 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876688 | 0.82 | FFAR4 (0.41) | MAPTEPHX2TRPV1 | |
| SCHEMBL24876183 | 0.79 | MEN1 (0.38) | MAPTHTR2CEPHX1CCNA2CDK2 | |
| SCHEMBL24875938 | 0.76 | MAPT (0.39) | MAPTEPHX1CCNA2CDK2CCNA1 | |
| SCHEMBL24876322 | 0.76 | MAPT (0.49) | MAPT | |
| SCHEMBL24876238 | 0.67 | PKM (0.34) | — | |
| SCHEMBL462640 | 0.65 | MAPT (0.54) | MAPTTRPV1 | |
| SCHEMBL31679994 | 0.64 | MAPT (0.47) | MAPT | |
| SCHEMBL23697541 | 0.62 | MAPT (0.49) | MAPTEPHX2FAAHTRPV1 | |
| SCHEMBL24875965 | 0.61 | MAPT (0.53) | MAPT | |
| SCHEMBL24876376 | 0.61 | MAPT (0.53) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |