Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.74 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | PKM | P14618 | 6/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | CDK1 | P06493 | 1/20 | 0.45 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.45 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 1/20 | 0.45 |
| ▸ | CDK7 | P50613 | 1/20 | 0.45 |
| ▸ | CCNH | P51946 | 1/20 | 0.45 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24876391 | 0.90 | LMNA (0.58) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL31679800 | 0.90 | LMNA (0.58) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL31680061 | 0.90 | THRB (0.69) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL24876316 | 0.90 | THRB (0.69) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL24876659 | 0.87 | LMNA (0.56) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL31680011 | 0.87 | LMNA (0.56) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL24876010 | 0.87 | LMNA (0.65) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL24876753 | 0.86 | LMNA (1.00) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL24876242 | 0.85 | LMNA (0.80) | LMNATHRBMEN1KMT2APKM | |
| SCHEMBL24876079 | 0.84 | THRB (0.65) | LMNATHRBMEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4367103-B1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | HELMHOLTZ ZENTRUM INFEKTIONSFORSCHUNG GMBH (DE) | 2025-09-03 | — | — | EP | disclosed |
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |