Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | THRB | P10828 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 5/20 | 0.46 |
| ▸ | SLC22A12 | Q96S37 | 4/20 | 0.45 |
| ▸ | BRD4 | O60885 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | P2RY4 | P51582 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31680011 | 1.00 | LMNA (0.56) | LMNATHRBPKMSLC22A12BRD4 | |
| SCHEMBL24876391 | 0.91 | LMNA (0.58) | LMNATHRBPKMSLC22A12BRD4 | |
| SCHEMBL31679800 | 0.91 | LMNA (0.58) | LMNATHRBPKMSLC22A12BRD4 | |
| SCHEMBL24876018 | 0.87 | LMNA (0.74) | LMNATHRBPKMKMT2AMEN1 | |
| SCHEMBL24876375 | 0.83 | LMNA (0.58) | LMNATHRBPKMBRD4KMT2A | |
| SCHEMBL31679859 | 0.82 | THRB (0.57) | LMNATHRBPKMBRD4KMT2A | |
| SCHEMBL24876665 | 0.82 | THRB (0.57) | LMNATHRBPKMBRD4KMT2A | |
| SCHEMBL24876630 | 0.80 | LMNA (0.54) | LMNATHRBPKMBRD4SGK1 | |
| SCHEMBL24876613 | 0.80 | LMNA (0.54) | LMNATHRBPKMBRD4KMT2A | |
| SCHEMBL31680027 | 0.80 | LMNA (0.54) | LMNATHRBPKMBRD4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023280970-A1 | INHIBITORS OF ALPHA-HEMOLYSIN OF STAPHYLOCOCCUS AUREUS | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2023-01-12 | — | — | WO | disclosed |